Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 2/20 | 0.53 |
| ▸ | SKP1 | P63208 | 2/20 | 0.53 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.53 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
| ▸ | RET | P07949 | 4/20 | 0.44 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22576378 | 1.00 | CKS1B (0.53) | CKS1BSKP1SKP2MAP4K4GPR119 | |
| SCHEMBL31254501 | 0.81 | CKS1B (0.63) | CKS1BSKP1SKP2MAP4K4GPR119 | |
| SCHEMBL1480048 | 0.81 | CKS1B (0.63) | CKS1BSKP1SKP2MAP4K4GPR119 | |
| SCHEMBL18163270 | 0.81 | CKS1B (0.48) | CKS1BSKP1SKP2MAP4K4GPR119 | |
| SCHEMBL1537817 | 0.80 | MAPT (0.53) | GPR119TGFBR1 | |
| SCHEMBL22576086 | 0.80 | JAK2 (0.49) | GPR119DDB1CRBNTGFBR1 | |
| SCHEMBL30456898 | 0.80 | JAK2 (0.49) | GPR119DDB1CRBNTGFBR1 | |
| SCHEMBL22766247 | 0.80 | CKS1B (0.56) | CKS1BSKP1SKP2RET | |
| SCHEMBL29819704 | 0.80 | CKS1B (0.56) | CKS1BSKP1SKP2RET | |
| SCHEMBL16249699 | 0.80 | PTPN11 (0.52) | CKS1BSKP1SKP2MAP4K4GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111699185-B | 6-azaindole compounds | 百时美施贵宝公司 | 2023-06-27 | — | — | CN | disclosed |