Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | HTR2C | P28335 | 2/20 | 0.52 |
| ▸ | HTR2B | P41595 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | HTR7 | P34969 | 5/20 | 0.48 |
| ▸ | DRD2 | P14416 | 3/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 3/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24227986 | 1.00 | HTR2A (0.52) | HTR2AHTR2CHTR2BKCNH2HTR7 | |
| SCHEMBL26192265 | 0.99 | HTR2A (0.53) | HTR2AHTR2CHTR2BKCNH2HTR7 | |
| SCHEMBL30503289 | 0.99 | HTR2A (0.53) | HTR2AHTR2CHTR2BKCNH2HTR7 | |
| SCHEMBL24228019 | 0.88 | MAOB (0.50) | HTR7MAPT | |
| SCHEMBL30503303 | 0.87 | PAOX (0.42) | HTR7DRD2DRD3SIGMAR1 | |
| SCHEMBL24228086 | 0.87 | PAOX (0.42) | HTR7DRD2DRD3SIGMAR1 | |
| SCHEMBL24227991 | 0.87 | MAOB (0.53) | HTR2AHTR2CHTR7DRD2DRD3 | |
| SCHEMBL30503331 | 0.87 | MAOB (0.53) | HTR2AHTR2CHTR7DRD2DRD3 | |
| SCHEMBL24228083 | 0.87 | CCR3 (0.50) | MAPT | |
| SCHEMBL30503278 | 0.86 | HTR1A (0.57) | HTR2AHTR2CKCNH2HTR7DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116472267-A | Butyrylcholinesterase reactivating agent | 法兰西国由中央军队卫生服务局代表 | 2023-07-21 | — | — | CN | disclosed |