Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 2/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | CLK3 | P49761 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26631464 | 1.00 | CDK5 (0.46) | CDK5CDK5R1CCNT1CCNA2CDK2 | |
| SCHEMBL28634050 | 0.79 | AXL (0.52) | CDK5CDK5R1CCNT1CCNA2CDK2 | |
| SCHEMBL5263827 | 0.77 | KMT2A (0.54) | CDK5CDK5R1CCNT1CCNA2CDK2 | |
| SCHEMBL15333269 | 0.76 | CDK5 (0.46) | CDK5CDK5R1CCNT1CCNA2CDK2 | |
| SCHEMBL29659275 | 0.76 | ADORA2A (0.40) | ADORA2AADORA1APP | |
| SCHEMBL20455615 | 0.76 | ADORA2A (0.40) | ADORA2AADORA1APP | |
| SCHEMBL20584686 | 0.76 | CDK5 (0.54) | CDK5CDK5R1CCNT1CCNA2CDK2 | |
| SCHEMBL21268783 | 0.76 | CCNT1 (0.43) | CDK5CDK5R1CCNT1CCNA2CDK2 | |
| SCHEMBL31365785 | 0.76 | CCNT1 (0.43) | CDK5CDK5R1CCNT1CCNA2CDK2 | |
| SCHEMBL13834754 | 0.72 | LRRK2 (0.53) | CDK5CDK5R1CCNT1CCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323557-A | Cyclobutylamide monoacylglycerol lipase modulators | 詹森药业有限公司 | 2023-06-23 | — | — | CN | disclosed |