Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.52 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.49 |
| ▸ | CDK9 | P50750 | 2/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.49 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.49 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | CLK3 | P49761 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14635390 | 0.79 | ADORA2A (0.50) | AXLADORA2AADORA1MEN1KMT2A | |
| SCHEMBL29605205 | 0.79 | ADORA2A (0.50) | AXLADORA2AADORA1MEN1KMT2A | |
| SCHEMBL30370261 | 0.79 | AXL (0.48) | AXLCCNT1CDK9CDK5CDK5R1 | |
| SCHEMBL20576173 | 0.79 | AXL (0.48) | AXLCCNT1CDK9CDK5CDK5R1 | |
| SCHEMBL21273862 | 0.79 | AXL (0.48) | AXLCCNT1CDK9CDK5CDK5R1 | |
| SCHEMBL20584686 | 0.79 | CDK5 (0.54) | AXLCCNT1CDK9CDK5CDK5R1 | |
| SCHEMBL15333269 | 0.79 | CDK5 (0.46) | AXLCCNT1CDK9CDK5CDK5R1 | |
| SCHEMBL30503527 | 0.79 | CDK5 (0.46) | AXLCCNT1CDK9CDK5CDK5R1 | |
| SCHEMBL5263827 | 0.76 | KMT2A (0.54) | CCNT1CDK9CDK5CDK5R1CCNA2 | |
| SCHEMBL21178475 | 0.75 | AXL (0.44) | AXLCCNT1CDK9CDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113264930-B | Pyrrole BET inhibitor and preparation method and application thereof | 中国药科大学 | 2022-07-29 | — | — | CN | disclosed |
| CN-113264930-A | Pyrrole BET inhibitor and preparation method and application thereof | 中国药科大学 | 2021-08-17 | — | — | CN | disclosed |