Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 2/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 2/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4569788 | 1.00 | AXL (0.41) | AXLNUDT1BRD4APPCDK8 | |
| SCHEMBL23970904 | 0.84 | AXL (0.38) | AXLNUDT1BRD4APPCDK8 | |
| SCHEMBL24248223 | 0.81 | AXL (0.36) | AXLNUDT1BRD4APPCDK8 | |
| SCHEMBL26525126 | 0.80 | — | — | |
| SCHEMBL29362564 | 0.79 | AXL (0.41) | AXLNUDT1BRD4APPCDK8 | |
| SCHEMBL20354682 | 0.79 | AXL (0.41) | AXLNUDT1BRD4APPCDK8 | |
| SCHEMBL20283841 | 0.79 | AXL (0.37) | AXLNUDT1BRD4APP | |
| SCHEMBL18924352 | 0.78 | TAS1R3 (0.37) | AXLNUDT1BRD4APP | |
| SCHEMBL24836072 | 0.78 | BRD4 (0.30) | BRD4 | |
| SCHEMBL21186513 | 0.78 | BRD4 (0.30) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323557-A | Cyclobutylamide monoacylglycerol lipase modulators | 詹森药业有限公司 | 2023-06-23 | — | — | CN | disclosed |