Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KCNN3 | Q9UGI6 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | TNKS | O95271 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26631311 | 1.00 | KDM4E (0.41) | KDM4ECYP3A4CYP2C19HIF1ALMNA | |
| SCHEMBL29697245 | 0.83 | HRH4 (0.36) | LMNAHRH4KCNN3HSD11B1 | |
| SCHEMBL22024527 | 0.83 | HRH4 (0.36) | LMNAHRH4KCNN3HSD11B1 | |
| SCHEMBL12754882 | 0.81 | CYP1A2 (0.42) | KDM4ELMNAHRH4POLBKCNN3 | |
| SCHEMBL30503520 | 0.80 | HRH4 (0.34) | HRH4 | |
| SCHEMBL26105826 | 0.80 | HRH4 (0.34) | HRH4 | |
| SCHEMBL30611847 | 0.80 | CYP2A6 (0.36) | KDM4ECYP3A4CYP2C19HIF1AHRH4 | |
| SCHEMBL26106551 | 0.80 | CYP2A6 (0.36) | KDM4ECYP3A4CYP2C19HIF1AHRH4 | |
| SCHEMBL31406243 | 0.78 | KDM4E (0.40) | KDM4ECYP3A4CYP2C19HIF1ALMNA | |
| SCHEMBL30611921 | 0.76 | HRH4 (0.32) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323557-A | Cyclobutylamide monoacylglycerol lipase modulators | 詹森药业有限公司 | 2023-06-23 | — | — | CN | disclosed |