Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 11/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31406222 | 0.83 | GRM2 (0.35) | GRM2HRH4 | |
| SCHEMBL31406227 | 0.81 | BACE1 (0.40) | GRM2HSP90AA1HRH4 | |
| SCHEMBL30503534 | 0.78 | KDM4E (0.41) | KDM4ECYP3A4CYP2C19HIF1ALMNA | |
| SCHEMBL26631311 | 0.78 | KDM4E (0.41) | KDM4ECYP3A4CYP2C19HIF1ALMNA | |
| SCHEMBL2540471 | 0.75 | KDM4E (0.40) | KDM4ECYP3A4CYP2C19HIF1AGRM2 | |
| SCHEMBL32682407 | 0.73 | GRM2 (0.36) | KDM4EGRM2LMNA | |
| SCHEMBL16548362 | 0.72 | CCR1 (0.38) | GRM2 | |
| SCHEMBL31406223 | 0.72 | PDE1A (0.43) | KDM4ECYP3A4CYP2C19HIF1A | |
| SCHEMBL30899670 | 0.71 | BRD9 (0.39) | — | |
| SCHEMBL30611846 | 0.70 | CYP19A1 (0.32) | KDM4ECYP3A4CYP2C19HIF1AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119562952-A | KIF18A inhibitors | 山东轩竹医药科技有限公司 | 2025-03-04 | — | — | CN | disclosed |