Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 3/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CCR1 | P32246 | 2/20 | 0.34 |
| ▸ | CCR5 | P51681 | 2/20 | 0.34 |
| ▸ | CCR8 | P51685 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28165722 | 1.00 | PDK2 (0.42) | PDK2GRIN1GRIN2AGRIN2BOPRM1 | |
| SCHEMBL9911858 | 0.80 | GRIN1 (0.42) | GRIN1GRIN2AGRIN2BOPRM1OPRD1 | |
| SCHEMBL31453965 | 0.74 | PDK2 (0.34) | PDK2OPRM1OPRL1 | |
| SCHEMBL17220961 | 0.73 | PDK2 (0.40) | PDK2GRIN1GRIN2AGRIN2BCHRM2 | |
| SCHEMBL29791494 | 0.72 | GRIN1 (0.46) | PDK2GRIN1GRIN2AGRIN2BOPRM1 | |
| SCHEMBL17506392 | 0.72 | KCNJ6 (0.37) | KDM4ESMN1; SMN2KCNJ6KCNJ5KCNJ3 | |
| SCHEMBL13805991 | 0.72 | UHRF1 (0.41) | PDK2OPRM1OPRL1KDM4ECCR1 | |
| SCHEMBL30701650 | 0.72 | KCNJ6 (0.37) | KDM4ESMN1; SMN2KCNJ6KCNJ5KCNJ3 | |
| SCHEMBL29006204 | 0.72 | GRIN1 (0.48) | GRIN1GRIN2AGRIN2BOPRM1OPRD1 | |
| SCHEMBL29730766 | 0.69 | GRIN1 (0.51) | PDK2GRIN1GRIN2AGRIN2BOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323557-A | Cyclobutylamide monoacylglycerol lipase modulators | 詹森药业有限公司 | 2023-06-23 | — | — | CN | disclosed |