Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ6 | P48051 | 2/20 | 0.37 |
| ▸ | KCNJ5 | P48544 | 2/20 | 0.37 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | WDR5 | P61964 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.31 |
| ▸ | RAF1 | P04049 | 1/20 | 0.30 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17506392 | 1.00 | KCNJ6 (0.37) | KCNJ6KCNJ5KCNJ3KDM4EALDH1A1 | |
| SCHEMBL28406039 | 0.79 | KDM4E (0.36) | KDM4EALDH1A1SMN1; SMN2SLC22A12 | |
| SCHEMBL27357711 | 0.79 | KCNJ6 (0.35) | KCNJ6KCNJ5KCNJ3PIK3CANOS3 | |
| SCHEMBL13805991 | 0.79 | UHRF1 (0.41) | KDM4EALDH1A1PIK3CANOS3NOS2 | |
| SCHEMBL17594690 | 0.77 | KDM4C (0.49) | KCNJ6KCNJ5KCNJ3KDM4EALDH1A1 | |
| SCHEMBL22558603 | 0.76 | KDM4E (0.37) | KDM4EALDH1A1SMN1; SMN2SLC22A12 | |
| SCHEMBL20890045 | 0.75 | NOS3 (0.43) | PIK3CANOS3NOS2RAF1KDM4C | |
| SCHEMBL25297918 | 0.73 | ALDH1A1 (0.34) | KCNJ6KCNJ5KCNJ3KDM4EALDH1A1 | |
| SCHEMBL30395366 | 0.73 | ALDH1A1 (0.34) | KCNJ6KCNJ5KCNJ3KDM4EALDH1A1 | |
| SCHEMBL13805990 | 0.72 | PIK3CA (0.39) | KDM4EALDH1A1PIK3CANOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4547657-A1 | CD73 COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2025-05-07 | — | — | EP | disclosed |
| CN-119384415-A | CD73 compounds | 吉利德科学公司 | 2025-01-28 | — | — | CN | disclosed |
| WO-2024006929-A1 | CD73 COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2024-01-04 | — | — | WO | disclosed |