Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 9/20 | 0.47 |
| ▸ | ABHD6 | Q9BV23 | 4/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | BCL9 | O00512 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26631491 | 1.00 | MGLL (0.47) | MGLLABHD6FAAHGPR119LIPE | |
| SCHEMBL29427036 | 1.00 | MGLL (0.47) | MGLLABHD6FAAHGPR119LIPE | |
| SCHEMBL29427132 | 1.00 | MGLL (0.47) | MGLLABHD6FAAHGPR119LIPE | |
| SCHEMBL25408234 | 0.86 | MGLL (0.49) | MGLLABHD6FAAHFFAR4 | |
| SCHEMBL23868006 | 0.86 | MGLL (0.58) | MGLLABHD6GPR119LIPE | |
| SCHEMBL29470023 | 0.86 | MGLL (0.58) | MGLLABHD6GPR119LIPE | |
| SCHEMBL29426777 | 0.83 | MGLL (0.54) | MGLLABHD6 | |
| SCHEMBL26631312 | 0.83 | PDE4B (0.40) | MGLLABHD6GPR119LIPERORC | |
| SCHEMBL29497506 | 0.83 | PDE4B (0.40) | MGLLABHD6GPR119LIPERORC | |
| SCHEMBL26738754 | 0.83 | MGLL (0.54) | MGLLABHD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323557-A | Cyclobutylamide monoacylglycerol lipase modulators | 詹森药业有限公司 | 2023-06-23 | — | — | CN | disclosed |