Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14747763 | 1.00 | CYP2D6 (0.41) | CYP2D6ADRA2AADRA1ACA1CA2 | |
| SCHEMBL28192492 | 0.86 | CA12 (0.40) | CYP2D6ADRA2AADRA1ACA1CA2 | |
| SCHEMBL1494189 | 0.82 | CYP2D6 (0.46) | CYP2D6ADRA2AADRA1ACA1CA2 | |
| SCHEMBL2242706 | 0.80 | SMN1; SMN2 (0.33) | MAPTALDH1A1KDM4E | |
| SCHEMBL23457049 | 0.80 | ADRA2A (0.47) | CYP2D6ADRA2AADRA1ACA1CA2 | |
| SCHEMBL31682604 | 0.80 | ADRA2A (0.47) | CYP2D6ADRA2AADRA1ACA1CA2 | |
| SCHEMBL500773 | 0.80 | CYP2D6 (0.41) | CYP2D6ADRA2AADRA1ACA1CA2 | |
| SCHEMBL17115832 | 0.79 | CYP2D6 (0.43) | CYP2D6ADRA2AADRA1ACA1CA2 | |
| SCHEMBL14691495 | 0.78 | ADRA2A (0.49) | CYP2D6ADRA2AADRA1AHPGDMEN1 | |
| SCHEMBL6796164 | 0.78 | ADRA2A (0.49) | CYP2D6ADRA2AADRA1AHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323557-A | Cyclobutylamide monoacylglycerol lipase modulators | 詹森药业有限公司 | 2023-06-23 | — | — | CN | disclosed |