Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 2/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | OXTR | P30559 | 1/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29497472 | 1.00 | DPP4 (0.39) | DPP4RORCGPR119HDAC2HDAC1 | |
| SCHEMBL29427000 | 1.00 | DPP4 (0.39) | DPP4RORCGPR119HDAC2HDAC1 | |
| SCHEMBL29427006 | 0.85 | DPP4 (0.38) | DPP4RORCHDAC2HDAC1ABHD6 | |
| SCHEMBL29024670 | 0.85 | DPP4 (0.38) | DPP4RORCHDAC2HDAC1ABHD6 | |
| SCHEMBL29497473 | 0.85 | DPP4 (0.38) | DPP4RORCHDAC2HDAC1ABHD6 | |
| SCHEMBL30503521 | 0.85 | DPP4 (0.38) | DPP4RORCHDAC2HDAC1ABHD6 | |
| SCHEMBL25436059 | 0.85 | FFAR4 (0.37) | MGLL | |
| SCHEMBL29497513 | 0.83 | HDAC2 (0.37) | DPP4HDAC2HDAC1ABHD6FAAH | |
| SCHEMBL29024807 | 0.83 | HDAC2 (0.37) | DPP4HDAC2HDAC1ABHD6FAAH | |
| SCHEMBL29427101 | 0.83 | HDAC2 (0.37) | DPP4HDAC2HDAC1ABHD6FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323557-A | Cyclobutylamide monoacylglycerol lipase modulators | 詹森药业有限公司 | 2023-06-23 | — | — | CN | disclosed |