Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 4/20 | 0.37 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | OXTR | P30559 | 1/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29024670 | 1.00 | DPP4 (0.38) | DPP4RORCHDAC2HDAC1MGLL | |
| SCHEMBL29497473 | 1.00 | DPP4 (0.38) | DPP4RORCHDAC2HDAC1MGLL | |
| SCHEMBL29427006 | 1.00 | DPP4 (0.38) | DPP4RORCHDAC2HDAC1MGLL | |
| SCHEMBL29427000 | 0.85 | DPP4 (0.39) | DPP4RORCHDAC2HDAC1MGLL | |
| SCHEMBL30503581 | 0.85 | DPP4 (0.39) | DPP4RORCHDAC2HDAC1MGLL | |
| SCHEMBL29497472 | 0.85 | DPP4 (0.39) | DPP4RORCHDAC2HDAC1MGLL | |
| SCHEMBL29427101 | 0.85 | HDAC2 (0.37) | DPP4HDAC2HDAC1MGLLABHD6 | |
| SCHEMBL29497513 | 0.85 | HDAC2 (0.37) | DPP4HDAC2HDAC1MGLLABHD6 | |
| SCHEMBL29024807 | 0.85 | HDAC2 (0.37) | DPP4HDAC2HDAC1MGLLABHD6 | |
| SCHEMBL25409300 | 0.83 | MGLL (0.38) | MGLLABHD6FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323557-A | Cyclobutylamide monoacylglycerol lipase modulators | 詹森药业有限公司 | 2023-06-23 | — | — | CN | disclosed |