Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | FYN | P06241 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2446676 | 1.00 | TRPA1 (0.56) | TRPA1ATMALDH1A1GABRA1GABRB2 | |
| SCHEMBL5512574 | 0.83 | TDP1 (0.45) | TRPA1ATMALDH1A1CA2HPGD | |
| SCHEMBL4090283 | 0.83 | CYP2A6 (0.43) | TRPA1ATMALDH1A1GABRA1GABRB2 | |
| SCHEMBL28179752 | 0.81 | TRPA1 (0.42) | TRPA1ATMALDH1A1GABRA1GABRB2 | |
| SCHEMBL6473329 | 0.79 | TRPA1 (0.58) | TRPA1ATMALDH1A1GABRA1GABRB2 | |
| SCHEMBL112587 | 0.79 | TRPA1 (0.58) | TRPA1ATMALDH1A1GABRA1GABRB2 | |
| SCHEMBL27700105 | 0.79 | ATM (0.58) | TRPA1ATMALDH1A1GABRA1GABRB2 | |
| SCHEMBL29664137 | 0.79 | TRPA1 (0.58) | TRPA1ATMALDH1A1GABRA1GABRB2 | |
| SCHEMBL6197878 | 0.79 | ESR1 (0.37) | TRPA1ATMALDH1A1HPGDHSD17B10 | |
| SCHEMBL11001536 | 0.78 | CYP1A2 (0.48) | TRPA1ATMALDH1A1GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323557-A | Cyclobutylamide monoacylglycerol lipase modulators | 詹森药业有限公司 | 2023-06-23 | — | — | CN | disclosed |