Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 6/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21812318 | 0.74 | AVPR1A (0.45) | AVPR1AOPRM1KCNH2 | |
| SCHEMBL30447969 | 0.73 | AVPR1A (0.50) | AVPR1AOPRM1KCNH2 | |
| SCHEMBL31415638 | 0.73 | AVPR1A (0.44) | AVPR1ASLC6A2OPRM1KCNH2 | |
| SCHEMBL24124835 | 0.72 | AVPR1A (0.31) | AVPR1A | |
| SCHEMBL30670269 | 0.72 | AVPR1A (0.49) | AVPR1AOPRL1OPRM1KCNH2 | |
| SCHEMBL26599110 | 0.72 | AVPR1A (0.49) | AVPR1AOPRL1OPRM1KCNH2 | |
| SCHEMBL31185772 | 0.71 | AVPR1A (0.40) | AVPR1AOPRM1KCNH2 | |
| SCHEMBL1588637 | 0.70 | AVPR1A (0.48) | AVPR1AOPRM1KCNH2KMT2A | |
| SCHEMBL29479156 | 0.70 | POLB (0.39) | AVPR1AL3MBTL1KMT2A | |
| SCHEMBL24373369 | 0.70 | POLB (0.39) | AVPR1AL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111527084-B | Isofuranone compounds useful as HPK1 inhibitors | 百时美施贵宝公司 | 2023-07-18 | — | — | CN | disclosed |