Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HBB | P68871 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22393852 | 1.00 | PGR (0.37) | PGRKMT2AIDH1CSNK2A2CSNK2B | |
| SCHEMBL25206708 | 0.81 | DAO (0.41) | PGRKMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL29936825 | 0.81 | DAO (0.41) | PGRKMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7032385 | 0.81 | MAPT (0.40) | KMT2AIDH1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL29937099 | 0.78 | MAP2 (0.42) | PGRALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL27142990 | 0.78 | MAP2 (0.42) | PGRALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL7026627 | 0.78 | IDH1 (0.35) | KMT2AIDH1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL17883917 | 0.78 | KDM4E (0.36) | IDH1CSNK2A2CSNK2BCSNK2A1ALDH1A1 | |
| SCHEMBL16167174 | 0.78 | GSK3B (0.39) | PGRIDH1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL25814975 | 0.76 | IDH1 (0.39) | KMT2AIDH1CSNK2A2CSNK2BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118302418-B | Aromatic heterocyclic compound and application thereof | 中国科学院上海药物研究所 | 2025-05-02 | — | — | CN | disclosed |
| US-20250042862-A1 | AROMATIC HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2025-02-06 | — | — | US | disclosed |
| EP-4431504-A1 | AROMATIC HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | Shanghai Institute of Material Medica, Chinese Academy of Sciences (CN) | 2024-09-18 | — | — | EP | disclosed |
| CN-118302418-A | Aromatic heterocyclic compound and application thereof | 中国科学院上海药物研究所 | 2024-07-05 | — | — | CN | disclosed |
| CN-116102533-A | Aromatic heterocyclic compound and application thereof | 中国科学院上海药物研究所 | 2023-05-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250042862-A1 | AROMATIC HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | KDM1B, KDM1A, KDM3B | PGR 1023/4885KMT2A 38/4885IDH1 92/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.