Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.76 |
| ▸ | MAOB | P27338 | 5/20 | 0.72 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | BCHE | P06276 | 4/20 | 0.61 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.58 |
| ▸ | RELA | Q04206 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30504733 | 0.86 | F3 (0.71) | MAOBMAPTLMNANPC1RAB9A | |
| SCHEMBL9420986 | 0.86 | MAOB (0.72) | ABCG2MAOBMAPTLMNACYP3A4 | |
| SCHEMBL14692575 | 0.86 | MAOB (0.72) | ABCG2MAOBMAPTLMNACYP3A4 | |
| SCHEMBL8987072 | 0.84 | MAOB (1.00) | ABCG2MAOBMAPTLMNANPC1 | |
| SCHEMBL8987069 | 0.84 | MAOB (1.00) | ABCG2MAOBMAPTLMNANPC1 | |
| SCHEMBL12871329 | 0.84 | ABCG2 (0.94) | ABCG2MAOBMAPTLMNANPC1 | |
| SCHEMBL1180393 | 0.84 | ABCG2 (0.94) | ABCG2MAOBMAPTLMNANPC1 | |
| SCHEMBL30504730 | 0.83 | ABCG2 (0.78) | ABCG2MAPTNPC1RAB9AMEN1 | |
| SCHEMBL30504735 | 0.83 | ABCG2 (0.73) | ABCG2MAOBMAPTLMNACYP1A2 | |
| SCHEMBL9341818 | 0.82 | ABCG2 (0.89) | ABCG2MAOBMAPTLMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116444359-B | Asymmetric double chalcone compound, synthesis method and application thereof | 温州医科大学附属眼视光医院 | 2025-03-18 | — | — | CN | disclosed |
| CN-116444359-A | Novel asymmetric double chalcone compound, synthesis method and application thereof | 温州医科大学附属眼视光医院 | 2023-07-18 | — | — | CN | disclosed |