Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25286353 | 1.00 | AR (0.43) | ARMRGPRX4HTTSMN1; SMN2 | |
| SCHEMBL30506562 | 0.80 | MRGPRX4 (0.53) | MRGPRX4 | |
| SCHEMBL17164241 | 0.80 | MRGPRX4 (0.53) | MRGPRX4 | |
| SCHEMBL25286930 | 0.79 | — | — | |
| SCHEMBL480938 | 0.78 | AR (0.50) | ARMRGPRX4HTTSMN1; SMN2 | |
| SCHEMBL17176478 | 0.77 | — | — | |
| SCHEMBL25765938 | 0.77 | — | — | |
| SCHEMBL17176151 | 0.75 | GRM2 (0.57) | MRGPRX4 | |
| SCHEMBL481150 | 0.75 | AR (0.46) | ARMRGPRX4HTTSMN1; SMN2 | |
| SCHEMBL17164317 | 0.74 | GRM2 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4452918-A1 | METABOTROPIC GLUTAMATE RECEPTOR POSITIVE ALLOSTERIC MODULATORS (PAMS) AND USES THEREOF | Sanford Burnham Prebys Medical Discovery Institute (US) | 2024-10-30 | — | — | EP | disclosed |
| WO-2023122276-A1 | METABOTROPIC GLUTAMATE RECEPTOR POSITIVE ALLOSTERIC MODULATORS (PAMS) AND USES THEREOF | Sanford Burnham Prebys Medical Discovery Institute (US) | 2023-06-29 | — | — | WO | disclosed |