Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25317930 | 1.00 | ALDH1A1 (0.44) | ALDH1A1NPSR1TDP1CYP11B1CYP11B2 | |
| SCHEMBL2695938 | 0.83 | ALDH1A1 (0.43) | ALDH1A1NPSR1TDP1CYP11B1CYP11B2 | |
| SCHEMBL32671133 | 0.80 | ALDH1A1 (0.46) | ALDH1A1NPSR1TDP1CYP11B1CYP11B2 | |
| SCHEMBL8629289 | 0.77 | MCHR1 (0.44) | RAB9A | |
| SCHEMBL2698969 | 0.76 | ALDH1A1 (0.49) | ALDH1A1NPSR1TDP1CYP11B1CYP11B2 | |
| SCHEMBL25318149 | 0.75 | CYP11B1 (0.31) | CYP11B1CYP11B2 | |
| SCHEMBL30507173 | 0.75 | ALDH1A1 (0.33) | ALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL25316662 | 0.75 | ALDH1A1 (0.33) | ALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL31178339 | 0.75 | CYP11B1 (0.31) | CYP11B1CYP11B2 | |
| SCHEMBL25217332 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4465982-A2 | APOL1 INHIBITORS AND METHODS OF USE | Maze Therapeutics, Inc. (US) | 2024-11-27 | — | — | EP | disclosed |
| WO-2023141432-A2 | APOL1 INHIBITORS AND METHODS OF USE | MAZE THERAPEUTICS, INC. (US) | 2023-07-27 | — | — | WO | disclosed |