Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.49 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.34 |
| ▸ | TLR4 | O00206 | 2/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.34 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30508251 | 1.00 | TLR8 (0.49) | TLR8HTR6IRAK4KDM2BTLR7 | |
| Hydrochloric Acid SCHEMBL30508246 | 0.99 | TLR8 (0.48) | TLR8HTR6IRAK4KDM2BTLR7 | |
| SCHEMBL20135108 | 0.92 | TLR8 (0.57) | TLR8IRAK4TLR7TLR4TLR9 | |
| Hydrochloric Acid SCHEMBL28215605 | 0.90 | TLR8 (0.56) | TLR8IRAK4TLR7TLR4TLR9 | |
| Hydrochloric Acid SCHEMBL30508248 | 0.90 | TLR8 (0.56) | TLR8IRAK4TLR7TLR4TLR9 | |
| SCHEMBL11890643 | 0.84 | TLR8 (0.44) | TLR8IRAK4 | |
| Trifluoroacetic Acid SCHEMBL25337241 | 0.80 | TLR8 (0.50) | TLR8IRAK4MET | |
| SCHEMBL29082025 | 0.80 | TLR8 (0.48) | TLR8IRAK4TLR7TLR4TLR9 | |
| SCHEMBL29083592 | 0.78 | TLR8 (0.37) | TLR8 | |
| SCHEMBL20135691 | 0.77 | TLR8 (0.57) | TLR8IRAK4TLR7TLR4TLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116478145-B | ALK2 kinase inhibitors | 杭州邦顺制药有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-116478145-A | ALK2 kinase inhibitors | 杭州邦顺制药有限公司 | 2023-07-25 | — | — | CN | disclosed |