Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMPR1B | O00238 | 14/20 | 0.49 |
| ▸ | BMPR1A | P36894 | 14/20 | 0.49 |
| ▸ | ACVRL1 | P37023 | 14/20 | 0.49 |
| ▸ | ACVR1 | Q04771 | 14/20 | 0.49 |
| ▸ | TGFBR1 | P36897 | 13/20 | 0.49 |
| ▸ | AXL | P30530 | 2/20 | 0.44 |
| ▸ | MERTK | Q12866 | 2/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.42 |
| ▸ | CLK2 | P49760 | 2/20 | 0.42 |
| ▸ | CLK3 | P49761 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30508341 | 0.91 | BMPR1B (0.49) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL30508328 | 0.89 | BMPR1B (0.61) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL30508410 | 0.88 | BMPR1B (0.60) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL30508221 | 0.86 | BMPR1B (0.52) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL30508295 | 0.86 | BMPR1B (0.61) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL30508184 | 0.86 | BMPR1B (0.61) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL30508299 | 0.86 | BMPR1B (0.61) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL30508183 | 0.86 | BMPR1B (0.61) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL30508377 | 0.79 | BMPR1B (0.61) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL30508332 | 0.78 | BMPR1B (0.51) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116478145-B | ALK2 kinase inhibitors | 杭州邦顺制药有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-116478145-A | ALK2 kinase inhibitors | 杭州邦顺制药有限公司 | 2023-07-25 | — | — | CN | disclosed |