Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMPR1B | O00238 | 19/20 | 0.66 |
| ▸ | BMPR1A | P36894 | 19/20 | 0.66 |
| ▸ | ACVRL1 | P37023 | 19/20 | 0.66 |
| ▸ | ACVR1 | Q04771 | 19/20 | 0.66 |
| ▸ | TGFBR1 | P36897 | 18/20 | 0.66 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29042037 | 1.00 | BMPR1B (0.66) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL19806984 | 0.89 | BMPR1B (0.77) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL19806932 | 0.89 | BMPR1B (0.77) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL19806896 | 0.88 | BMPR1B (0.79) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL30508267 | 0.84 | BMPR1B (0.61) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL23418645 | 0.82 | BMPR1B (0.86) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL19806985 | 0.82 | BMPR1B (0.86) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL20995128 | 0.80 | BMPR1B (1.00) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL20995142 | 0.80 | BMPR1B (1.00) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL21026974 | 0.80 | BMPR1B (1.00) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116478145-B | ALK2 kinase inhibitors | 杭州邦顺制药有限公司 | 2024-02-02 | — | — | CN | disclosed |
| WO-2023198114-A1 | ALK2 KINASE INHIBITOR | 杭州邦顺制药有限公司 | 2023-10-19 | — | — | WO | disclosed |
| CN-116478145-A | ALK2 kinase inhibitors | 杭州邦顺制药有限公司 | 2023-07-25 | — | — | CN | disclosed |