Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMPR1B | O00238 | 13/20 | 0.43 |
| ▸ | BMPR1A | P36894 | 13/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 13/20 | 0.43 |
| ▸ | ACVRL1 | P37023 | 13/20 | 0.43 |
| ▸ | ACVR1 | Q04771 | 13/20 | 0.43 |
| ▸ | GHSR | Q92847 | 1/20 | 0.42 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.42 |
| ▸ | MET | P08581 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.40 |
| ▸ | MST1R | Q04912 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29152377 | 1.00 | BMPR1B (0.43) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL29042048 | 0.94 | BMPR1B (0.42) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL30508273 | 0.94 | BMPR1B (0.42) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL30508371 | 0.89 | MAP4K4 (0.43) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL30508244 | 0.83 | PIK3C3 (0.43) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL30508206 | 0.83 | ACVR1 (0.42) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL29041972 | 0.83 | PIK3C3 (0.43) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL30508209 | 0.83 | BMPR1B (0.62) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL30508286 | 0.82 | PIK3C3 (0.53) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL29042035 | 0.82 | PIK3C3 (0.53) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116478145-B | ALK2 kinase inhibitors | 杭州邦顺制药有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-116478145-A | ALK2 kinase inhibitors | 杭州邦顺制药有限公司 | 2023-07-25 | — | — | CN | disclosed |