Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | F3 | P13726 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21616999 | 1.00 | SMN1; SMN2 (0.36) | SMN1; SMN2NPC1RAB9AKMT2AKCNA5 | |
| SCHEMBL29486220 | 0.97 | SMN1; SMN2 (0.38) | SMN1; SMN2NPC1RAB9AKMT2AKCNA5 | |
| SCHEMBL22899612 | 0.97 | SMN1; SMN2 (0.38) | SMN1; SMN2NPC1RAB9AKMT2AKCNA5 | |
| SCHEMBL21617010 | 0.94 | GPR52 (0.33) | SMN1; SMN2NPC1RAB9AKMT2AKCNA5 | |
| SCHEMBL22899346 | 0.90 | GPR52 (0.36) | SMN1; SMN2NPC1RAB9AKMT2AKCNA5 | |
| SCHEMBL29486081 | 0.90 | GPR52 (0.36) | SMN1; SMN2NPC1RAB9AKMT2AKCNA5 | |
| SCHEMBL29486137 | 0.89 | SMN1; SMN2 (0.35) | SMN1; SMN2NPC1RAB9AKMT2AKCNA5 | |
| SCHEMBL22899343 | 0.89 | SMN1; SMN2 (0.35) | SMN1; SMN2NPC1RAB9AKMT2AKCNA5 | |
| SCHEMBL22899408 | 0.88 | HPGD (0.35) | SMN1; SMN2NPC1RAB9AKCNA5HPGD | |
| SCHEMBL29486075 | 0.88 | HPGD (0.35) | SMN1; SMN2NPC1RAB9AKCNA5HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3820849-B1 | PHENYL/PYRIDYL-NH-PHENYL/PYRIDYL DERIVATIVES FOR TREATING RNA VIRUS INFECTION | ABIVAX (FR) | 2023-09-06 | — | — | EP | disclosed |