Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 2/20 | 0.32 |
| ▸ | CDK9 | P50750 | 2/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.31 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.31 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29088905 | 1.00 | CCNT1 (0.32) | CCNT1CDK9FLT3PIK3CANTRK1 | |
| SCHEMBL29088980 | 0.75 | NTRK1 (0.42) | CCNT1CDK9FLT3PIK3CANTRK1 | |
| SCHEMBL21838100 | 0.70 | NTRK1 (0.47) | NTRK1 | |
| SCHEMBL29088974 | 0.69 | NTRK1 (0.40) | CCNT1CDK9FLT3PIK3CANTRK1 | |
| SCHEMBL29088901 | 0.69 | NTRK1 (0.38) | CCNT1CDK9FLT3PIK3CANTRK1 | |
| SCHEMBL29088983 | 0.68 | NPC1 (0.40) | CCNT1CDK9FLT3PIK3CANTRK1 | |
| SCHEMBL29088919 | 0.67 | NTRK1 (0.47) | NTRK1NTRK3NTRK2 | |
| SCHEMBL16946781 | 0.67 | NTRK1 (0.46) | NTRK1 | |
| SCHEMBL30761741 | 0.66 | NTRK1 (0.57) | NTRK1 | |
| SCHEMBL28346740 | 0.66 | NTRK1 (0.57) | NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110156813-B | Heterocyclic compounds as TRK inhibitors | 北京诺诚健华医药科技有限公司 | 2023-07-25 | — | — | CN | disclosed |