Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 2/20 | 0.55 |
| ▸ | CALCRL | Q16602 | 4/20 | 0.50 |
| ▸ | F11 | P03951 | 1/20 | 0.50 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.49 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 2/20 | 0.49 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.49 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.48 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.48 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.48 |
| ▸ | APLNR | P35414 | 1/20 | 0.47 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31280950 | 0.87 | MAPK8 (0.53) | EPHA2CALCRLF11MAPK8MAPK9 | |
| SCHEMBL30567785 | 0.86 | GLP1R (0.57) | KDM1AAPLNR | |
| SCHEMBL31282086 | 0.84 | SLC6A2 (0.58) | EPHA2CALCRLMAPK8MAPK9MAPK10 | |
| SCHEMBL30804662 | 0.84 | MAPK8 (0.56) | EPHA2MAPK8MAPK9MAPK10NMUR2 | |
| SCHEMBL31410846 | 0.84 | EPHA2 (0.58) | EPHA2KDM1AC5AR1OPRM1 | |
| SCHEMBL31034420 | 0.84 | NPY2R (0.55) | KDM1AC5AR1APLNRIL23R | |
| SCHEMBL31281064 | 0.83 | MAPK8 (0.56) | EPHA2CALCRLMAPK8MAPK9MAPK10 | |
| SCHEMBL31307255 | 0.83 | EPHA2 (0.58) | EPHA2C5AR1NMUR2NMUR1 | |
| SCHEMBL29531483 | 0.83 | EPHA2 (0.51) | EPHA2NMUR2NMUR1OPRM1OPRK1 | |
| SCHEMBL31572089 | 0.83 | EPHA2 (0.61) | EPHA2CALCRLMAPK8MAPK9MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116490215-A | Targeted mediated endocytic drug delivery | CRM医疗有限公司 | 2023-07-25 | — | — | CN | disclosed |