Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 2/20 | 0.51 |
| ▸ | NMUR2 | Q9GZQ4 | 4/20 | 0.50 |
| ▸ | NMUR1 | Q9HB89 | 4/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.50 |
| ▸ | ACE | P12821 | 2/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.49 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30457966 | 0.88 | MAPK8 (0.53) | OPRM1OPRD1OPRK1 | |
| SCHEMBL30974592 | 0.87 | F2 (0.58) | EPHA2OPRM1OPRD1OPRK1F2 | |
| SCHEMBL30405782 | 0.86 | NMUR2 (0.57) | EPHA2NMUR2NMUR1OPRM1OPRD1 | |
| SCHEMBL30693083 | 0.85 | F2 (0.58) | EPHA2OPRM1OPRD1OPRK1F2 | |
| SCHEMBL30782709 | 0.85 | OPRM1 (0.62) | EPHA2NMUR2NMUR1OPRM1OPRD1 | |
| SCHEMBL31099137 | 0.85 | OPRM1 (0.57) | EPHA2NMUR2NMUR1OPRM1OPRD1 | |
| SCHEMBL31410880 | 0.84 | OPRM1 (0.58) | EPHA2NMUR2NMUR1OPRM1OPRD1 | |
| SCHEMBL11600367 | 0.84 | F2 (0.51) | EPHA2NMUR2NMUR1OPRM1OPRD1 | |
| SCHEMBL8529458 | 0.84 | F2 (0.51) | EPHA2NMUR2NMUR1OPRM1OPRD1 | |
| SCHEMBL30974475 | 0.84 | EPHA2 (0.57) | EPHA2NMUR2NMUR1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230393140-A1 | BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS | SRI INTERNATIONAL (US) | 2023-12-07 | — | — | US | disclosed |
| EP-4229211-A1 | BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS | SRI International (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022082006-A1 | BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS | SRI INTERNATIONAL (US) | 2022-04-21 | — | — | WO | disclosed |