Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.39 |
| ▸ | NT5E | P21589 | 5/20 | 0.38 |
| ▸ | DPYD | Q12882 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13314271 | 1.00 | ALDH1A1 (0.50) | ALDH1A1LMNAPRMT5WDR77ROCK2 | |
| Hydrochloric Acid SCHEMBL3561066 | 0.98 | ALDH1A1 (0.49) | ALDH1A1LMNAPRMT5WDR77ROCK2 | |
| SCHEMBL8675092 | 0.78 | ALDH1A1 (0.56) | ALDH1A1LMNAROCK2ROCK1CDC42BPB | |
| SCHEMBL1555373 | 0.73 | ALDH1A1 (0.50) | ALDH1A1LMNANT5EDPYDGAA | |
| SCHEMBL24300828 | 0.73 | HTT (0.50) | ALDH1A1LMNANT5EDPYDGAA | |
| SCHEMBL13314211 | 0.72 | ALDH1A1 (0.49) | ALDH1A1LMNADPYDGAAATAD2 | |
| SCHEMBL13314195 | 0.72 | ALDH1A1 (0.49) | ALDH1A1LMNANT5EDPYDGAA | |
| SCHEMBL3559799 | 0.72 | ALDH1A1 (0.49) | ALDH1A1LMNANT5EATAD2 | |
| Hydrochloric Acid SCHEMBL3566887 | 0.71 | ALDH1A1 (0.47) | ALDH1A1LMNANT5EDPYDGAA | |
| Hydrochloric Acid SCHEMBL3558331 | 0.71 | ALDH1A1 (0.47) | ALDH1A1LMNANT5EATAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023138612-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS HPK1 INHIBITORS | SILEXON AI TECHNOLOGY CO., LTD. (CN) | 2023-07-27 | — | — | WO | disclosed |