Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.39 |
| ▸ | S100A4 | P26447 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | BCL2 | P10415 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30512991 | 1.00 | PBRM1 (0.39) | PBRM1S100A4PTPRCMAPK1CYP1A2 | |
| SCHEMBL25409901 | 1.00 | PBRM1 (0.39) | PBRM1S100A4PTPRCMAPK1CYP1A2 | |
| SCHEMBL25411311 | 1.00 | PBRM1 (0.39) | PBRM1S100A4PTPRCMAPK1CYP1A2 | |
| SCHEMBL25409903 | 1.00 | PBRM1 (0.39) | PBRM1S100A4PTPRCMAPK1CYP1A2 | |
| SCHEMBL2729079 | 0.80 | PBRM1 (0.42) | PBRM1S100A4PTPRCMAPK1CYP1A2 | |
| SCHEMBL30553000 | 0.80 | PBRM1 (0.42) | PBRM1S100A4PTPRCMAPK1CYP1A2 | |
| SCHEMBL86917 | 0.74 | S100A4 (0.42) | PBRM1S100A4PTPRCMAPK1CYP1A2 | |
| SCHEMBL10254108 | 0.73 | S100A4 (0.41) | PBRM1S100A4PTPRCMAPK1CYP1A2 | |
| SCHEMBL18705382 | 0.73 | S100A4 (0.41) | PBRM1S100A4PTPRCMAPK1CYP1A2 | |
| SCHEMBL2532868 | 0.73 | S100A4 (0.41) | PBRM1S100A4PTPRCMAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023138612-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS HPK1 INHIBITORS | SILEXON AI TECHNOLOGY CO., LTD. (CN) | 2023-07-27 | — | — | WO | disclosed |