Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | NAMPT | P43490 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15178963 | 0.86 | KMT2A (0.62) | NPC1KMT2AMEN1L3MBTL1POLB | |
| SCHEMBL18181909 | 0.83 | NPC1 (0.70) | NPC1KMT2AMEN1L3MBTL1POLB | |
| SCHEMBL30513371 | 0.82 | CYP2D6 (0.61) | NPC1KMT2AMEN1L3MBTL1POLB | |
| SCHEMBL3300404 | 0.79 | ALDH1A1 (0.84) | NPC1KMT2AMEN1L3MBTL1LMNA | |
| SCHEMBL6334539 | 0.79 | KMT2A (0.60) | NPC1KMT2AMEN1L3MBTL1POLB | |
| SCHEMBL6334532 | 0.79 | KMT2A (0.60) | NPC1KMT2AMEN1L3MBTL1POLB | |
| SCHEMBL4070839 | 0.78 | ALDH1A1 (0.84) | NPC1KMT2AMEN1L3MBTL1LMNA | |
| SCHEMBL21464791 | 0.78 | KMT2A (0.65) | NPC1KMT2AMEN1POLBLMNA | |
| SCHEMBL21464804 | 0.78 | KMT2A (0.69) | NPC1KMT2AMEN1POLBLMNA | |
| SCHEMBL4759272 | 0.77 | KMT2A (0.78) | KMT2AMEN1L3MBTL1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119330892-A | Benzenesulfonamide derivative and preparation method and application thereof | 天津科技大学 | 2025-01-21 | — | — | CN | disclosed |
| CN-116496292-A | Benzenesulfonamide derivative and preparation method and application thereof | 天津科技大学 | 2023-07-28 | — | — | CN | disclosed |