Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.70 |
| ▸ | CASP7 | P55210 | 1/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.70 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.59 |
| ▸ | TYMS | P04818 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL460333 | 1.00 | CASP1 (0.70) | CASP1CASP7HSD17B10PBRM1TYMS | |
| Hydrochloric Acid SCHEMBL3873080 | 0.98 | CASP1 (0.68) | CASP1CASP7HSD17B10PBRM1TYMS | |
| SCHEMBL656011 | 0.88 | CASP1 (0.55) | CASP1CASP7HSD17B10PBRM1TYMS | |
| SCHEMBL30067461 | 0.88 | CASP1 (0.55) | CASP1CASP7HSD17B10PBRM1TYMS | |
| SCHEMBL4878376 | 0.88 | CASP1 (0.55) | CASP1CASP7HSD17B10PBRM1TYMS | |
| SCHEMBL16559372 | 0.84 | CASP1 (0.55) | CASP1CASP7HSD17B10PBRM1TYMS | |
| SCHEMBL434358 | 0.83 | CASP1 (1.00) | CASP1CASP7HSD17B10PBRM1CA9 | |
| Hydrochloric Acid SCHEMBL27821207 | 0.81 | CASP1 (0.96) | CASP1CASP7HSD17B10PBRM1CA9 | |
| SCHEMBL3278777 | 0.80 | MAPT (0.54) | CASP1CASP7HSD17B10TYMSCA9 | |
| SCHEMBL6362924 | 0.80 | CASP1 (0.47) | CASP1CASP7HSD17B10PBRM1TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054339-A1 | TRIAZOLOPYRIDINE COMPOUNDS AS INHIBITORS OF KIT | ARCUS BIOSCIENCES, INC. (US) | 2025-03-13 | — | — | WO | disclosed |
| CN-118546121-A | Compounds as Kif18A inhibitors | 江苏星盛新辉医药有限公司 | 2024-08-27 | — | — | CN | disclosed |
| CN-112759549-B | 3-substituted amino-4- ((substituted pyridinyl) amino) cyclobut-3-ene-1, 2-dione compounds | 中国医学科学院药物研究所 | 2023-07-28 | — | — | CN | disclosed |