SCHEMBL30513619

SCHEMBL30513619

CC(C)(C)c1ccccc1Oc1cc(Br)cc(Oc2ccccc2C(C)(C)C)c1Br

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 7/20 0.39
TDP1 Q9NUW8 2/20 0.37
ATM Q13315 1/20 0.37
MAPT P10636 1/20 0.37
P2RY1 P47900 5/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36
HSD17B10 Q99714 1/20 0.36
ALDH1A1 P00352 4/20 0.35
TSHR P16473 1/20 0.35
NR1I2 O75469 1/20 0.35
CYP2C8 P10632 1/20 0.35
KDM4E B2RXH2 2/20 0.35
GAA P10253 1/20 0.35
RXRA P19793 1/20 0.35
RXRB P28702 1/20 0.35
RXRG P48443 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30513618 1.00 IDO1 (0.39) IDO1TDP1ATMMAPTP2RY1
SCHEMBL30500977 0.82 ALDH1A1 (0.48) TDP1ATMMAPTP2RY1CYP1A2
SCHEMBL127278 0.82 ALDH1A1 (0.48) TDP1ATMMAPTP2RY1CYP1A2
SCHEMBL16177728 0.79 TDP1 (0.40) IDO1TDP1ATMMAPTP2RY1
SCHEMBL7040375 0.79 IDO1 (0.41) IDO1TDP1P2RY1ALDH1A1NR1I2
SCHEMBL16344881 0.77 IDO1 (0.41) IDO1TDP1ATMP2RY1CYP1A2
SCHEMBL7044342 0.75 AR (0.40) IDO1TDP1ATMMAPTALDH1A1
SCHEMBL12793242 0.73 MRGPRX4 (0.43) IDO1TDP1ATMP2RY1CYP1A2
SCHEMBL397028 0.72 ALDH1A1 (0.48) TDP1ATMMAPTP2RY1CYP1A2
SCHEMBL11429277 0.72 SLC6A2 (0.47) IDO1TDP1ATMP2RY1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116478197-A Triarylboron derivative based on oxygen bridging, and preparation method and application thereof 天津大学 2023-07-25 CN disclosed