Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPS1 | P31327 | 14/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3502022 | 0.86 | CPS1 (0.58) | CPS1HPGDALDH1A1MEN1LMNA | |
| SCHEMBL14519861 | 0.81 | NPC1 (0.60) | HPGDALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL3484699 | 0.81 | NPC1 (0.49) | HPGDALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL3639792 | 0.81 | NPC1 (0.68) | HPGDALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL757099 | 0.81 | HTT (0.55) | HPGDALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL29639738 | 0.80 | ALDH1A1 (0.65) | CPS1HPGDALDH1A1MEN1LMNA | |
| SCHEMBL531399 | 0.80 | ALDH1A1 (0.65) | CPS1HPGDALDH1A1MEN1LMNA | |
| SCHEMBL1051747 | 0.80 | CPS1 (0.63) | CPS1HPGDALDH1A1MEN1LMNA | |
| SCHEMBL9559907 | 0.79 | ALDH1A1 (0.49) | HPGDALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL26440433 | 0.79 | LIMK1 (0.49) | HPGDALDH1A1MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116496258-A | Carboxylic acid compound, preparation method thereof and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2023-07-28 | — | — | CN | disclosed |