Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10330507 | 0.87 | KMT2A (0.59) | KMT2AHDAC6TSHRMAPK1HPGD | |
| SCHEMBL10330500 | 0.85 | KMT2A (0.58) | KMT2AHDAC6TSHRMAPK1HPGD | |
| SCHEMBL20858854 | 0.84 | KMT2A (0.60) | KMT2AHDAC6TSHRMAPK1HPGD | |
| SCHEMBL10269519 | 0.83 | KMT2A (0.63) | KMT2AHDAC6TSHRMAPK1HPGD | |
| SCHEMBL2228382 | 0.83 | KMT2A (0.63) | KMT2AHDAC6TSHRMAPK1HPGD | |
| SCHEMBL15108850 | 0.81 | KMT2A (0.61) | KMT2AHDAC6TSHRMAPK1HPGD | |
| SCHEMBL14454157 | 0.81 | KMT2A (0.61) | KMT2AHDAC6TSHRMAPK1HPGD | |
| SCHEMBL29062257 | 0.80 | CDK4 (0.55) | HDAC6HPGDGAASMN1; SMN2TP53 | |
| SCHEMBL19204050 | 0.79 | KMT2A (0.67) | KMT2ATSHRMAPK1HPGDMEN1 | |
| SCHEMBL15343524 | 0.79 | KMT2A (0.67) | KMT2ATSHRMAPK1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111868063-B | PI4KIII beta inhibitors | 葛兰素史克知识产权开发有限公司 | 2023-08-01 | — | — | CN | claimed |