⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25322588 | 1.00 | — | — | |
| SCHEMBL25321474 | 1.00 | — | — | |
| SCHEMBL29082027 | 0.89 | LOXL2 (0.33) | — | |
| SCHEMBL24367600 | 0.84 | HDAC6 (0.32) | — | |
| SCHEMBL30471172 | 0.84 | HDAC6 (0.32) | — | |
| SCHEMBL24366026 | 0.84 | HDAC6 (0.32) | — | |
| SCHEMBL32689101 | 0.84 | HDAC6 (0.32) | — | |
| SCHEMBL32689015 | 0.83 | HDAC6 (0.41) | — | |
| SCHEMBL24364976 | 0.83 | HDAC6 (0.41) | — | |
| SCHEMBL29081633 | 0.83 | HDAC6 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4469455-A1 | COMPOUNDS AND METHODS OF USE | Tango Therapeutics, Inc. (US) | 2024-12-04 | — | — | EP | disclosed |
| EP-4469447-A1 | COMPOUNDS AND METHODS OF USE | Tango Therapeutics, Inc. (US) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023146990-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023146989-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |