Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.58 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.50 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.50 |
| ▸ | RET | P07949 | 4/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.49 |
| ▸ | CKS1B | P61024 | 2/20 | 0.48 |
| ▸ | SKP1 | P63208 | 2/20 | 0.48 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.44 |
| ▸ | ADK | P55263 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL182911 | 1.00 | USP30 (0.58) | USP30DDB1CRBNRETGPR119 | |
| SCHEMBL30746202 | 0.92 | USP30 (0.54) | USP30DDB1CRBNRETGPR119 | |
| SCHEMBL31541392 | 0.89 | USP30 (0.54) | USP30DDB1CRBNRETDGAT1 | |
| SCHEMBL25175468 | 0.88 | USP30 (0.55) | USP30DDB1CRBNRETGPR119 | |
| SCHEMBL30376562 | 0.88 | USP30 (0.55) | USP30DDB1CRBNRETGPR119 | |
| SCHEMBL31583702 | 0.88 | USP30 (0.53) | USP30DDB1CRBNRETGPR119 | |
| SCHEMBL24623333 | 0.86 | USP30 (0.58) | USP30DDB1CRBNRETGPR119 | |
| SCHEMBL25175509 | 0.86 | DDB1 (0.48) | USP30DDB1CRBNRETGPR119 | |
| SCHEMBL30376885 | 0.86 | DDB1 (0.48) | USP30DDB1CRBNRETGPR119 | |
| SCHEMBL4252998 | 0.86 | DDB1 (0.46) | USP30DDB1CRBNRETGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025077891-A1 | DEGRADATION AGENT COMPOUND TARGETING IRAK4, AND USE THEREOF | 江苏先声药业有限公司 | 2025-04-17 | — | — | WO | disclosed |
| WO-2024199341-A1 | FUSED POLYCYCLIC DERIVATIVE AND USE THEREOF | 浙江海正药业股份有限公司 | 2024-10-03 | — | — | WO | disclosed |
| CN-116514779-A | 2, 4-disubstituted-5-fluoropyrimidine derivative and preparation method and application thereof | 中南大学 | 2023-08-01 | — | — | CN | disclosed |