Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 3/20 | 0.36 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PLAT | P00750 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.32 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9869560 | 0.90 | RIPK2 (0.38) | NNMTRIPK2TSHRPLATKDM4E | |
| Hydrochloric Acid SCHEMBL28692305 | 0.89 | RIPK2 (0.37) | NNMTRIPK2TSHRPLATKDM4E | |
| SCHEMBL9869341 | 0.75 | POLB (0.38) | RIPK2PLATKDM4ETDP1L3MBTL1 | |
| SCHEMBL23778840 | 0.73 | AURKA (0.46) | NNMTRIPK2TSHRPLATTLR8 | |
| Sulfuric Acid SCHEMBL4196997 | 0.71 | RAD52 (0.31) | — | |
| SCHEMBL9728839 | 0.70 | PLAT (0.36) | NNMTRIPK2TSHRPLATKDM4E | |
| SCHEMBL29710603 | 0.70 | KDM4E (0.37) | RIPK2KDM4EMAP2K1CLK4DYRK1B | |
| SCHEMBL29710592 | 0.69 | LCK (0.41) | RIPK2 | |
| SCHEMBL9020642 | 0.68 | — | — | |
| SCHEMBL10554145 | 0.68 | MAPK14 (0.43) | TSHRGAAPARP1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514806-A | Biological inhibitor containing acrylketone, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-08-01 | — | — | CN | disclosed |