Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAT | P00750 | 2/20 | 0.36 |
| ▸ | NNMT | P40261 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30515902 | 0.70 | NNMT (0.36) | PLATNNMTKDM4EGAARECQL | |
| SCHEMBL9869560 | 0.68 | RIPK2 (0.38) | PLATNNMTKDM4EGAARECQL | |
| Hydrochloric Acid SCHEMBL28692305 | 0.67 | RIPK2 (0.37) | PLATNNMTKDM4EGAARECQL | |
| SCHEMBL30335668 | 0.65 | KDM4E (0.55) | KDM4EGAARECQLJAK2JAK1 | |
| SCHEMBL8335601 | 0.64 | RIPK2 (0.46) | KDM4ERIPK2MAP2K1CLK4DYRK1B | |
| SCHEMBL30718275 | 0.64 | BTK (0.47) | PLATKDM4EGAARECQLCHRNB2 | |
| SCHEMBL1155431 | 0.59 | — | — | |
| SCHEMBL23778840 | 0.58 | AURKA (0.46) | PLATNNMTRIPK2CHRNB2CHRNA4 | |
| SCHEMBL30688555 | 0.58 | SIRT3 (0.38) | NNMTSIRT3TDP1PARP1TSHR | |
| SCHEMBL31678255 | 0.58 | SIRT3 (0.38) | NNMTSIRT3TDP1PARP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169850-A | Neurotropic or hypotensive agents | AMERICAN CYANAMID COMPANY (US) | 1992-12-08 | — | — | US | disclosed |
| US-5059691-A | Anxiolytic agents; hypotensive agents; nervous system disorders; cognition activators | AMERICAN CYANAMID COMPANY (US) | 1991-10-22 | — | — | US | disclosed |