Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 2/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 13/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 6/20 | 0.39 |
| ▸ | PARP6 | Q2NL67 | 4/20 | 0.39 |
| ▸ | PARP3 | Q9Y6F1 | 4/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24649798 | 1.00 | MEN1 (0.46) | MEN1MAPTTSHRKMT2ASMN1; SMN2 | |
| SCHEMBL24649800 | 0.90 | JAK3 (0.45) | MEN1MAPTTSHRKMT2ASMN1; SMN2 | |
| SCHEMBL25738416 | 0.89 | MEN1 (0.48) | MEN1MAPTTSHRKMT2ASMN1; SMN2 | |
| SCHEMBL20838957 | 0.85 | JAK3 (0.44) | MEN1MAPTTSHRKMT2ASMN1; SMN2 | |
| SCHEMBL30558294 | 0.85 | JAK3 (0.44) | MEN1MAPTTSHRKMT2ASMN1; SMN2 | |
| SCHEMBL20848279 | 0.84 | JAK3 (0.46) | MEN1MAPTTSHRKMT2ASMN1; SMN2 | |
| SCHEMBL20839065 | 0.83 | JAK3 (0.46) | MEN1MAPTTSHRKMT2ASMN1; SMN2 | |
| SCHEMBL30558296 | 0.83 | JAK3 (0.46) | MEN1MAPTTSHRKMT2ASMN1; SMN2 | |
| SCHEMBL22912831 | 0.82 | SMN1; SMN2 (0.65) | MEN1MAPTTSHRKMT2ASMN1; SMN2 | |
| SCHEMBL29396475 | 0.82 | SMN1; SMN2 (0.65) | MEN1MAPTTSHRKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232121-B | Pyridine derivative and application thereof in medicine | 成都百裕制药股份有限公司 | 2023-08-29 | — | — | CN | disclosed |