Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 6/20 | 1.00 |
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | LMNA | P02545 | 4/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 1.00 |
| ▸ | NPC1 | O15118 | 7/20 | 0.69 |
| ▸ | RAB9A | P51151 | 7/20 | 0.69 |
| ▸ | POLB | P06746 | 3/20 | 0.69 |
| ▸ | CASP3 | P42574 | 2/20 | 0.69 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.69 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | RAF1 | P04049 | 1/20 | 0.61 |
| ▸ | CDK8 | P49336 | 1/20 | 0.60 |
| ▸ | KDR | P35968 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20211616 | 1.00 | MEN1 (1.00) | MEN1KMT2AMAPTLMNANPSR1 | |
| SCHEMBL8104826 | 0.88 | KMT2A (0.78) | MEN1KMT2AMAPTLMNANPSR1 | |
| SCHEMBL28863260 | 0.86 | CDK8 (0.83) | MEN1KMT2AMAPTLMNANPSR1 | |
| SCHEMBL4347494 | 0.86 | MEN1 (0.74) | MEN1KMT2AMAPTLMNANPSR1 | |
| SCHEMBL10712301 | 0.85 | MEN1 (0.76) | MEN1KMT2AMAPTLMNANPSR1 | |
| SCHEMBL1700678 | 0.84 | MEN1 (0.87) | MEN1KMT2AMAPTLMNANPSR1 | |
| SCHEMBL4118510 | 0.84 | KMT2A (0.72) | MEN1KMT2AMAPTLMNANPSR1 | |
| SCHEMBL22263059 | 0.84 | MEN1 (0.72) | MEN1KMT2AMAPTLMNANPSR1 | |
| SCHEMBL11847456 | 0.84 | MAPT (0.72) | MEN1KMT2AMAPTLMNANPSR1 | |
| SCHEMBL24272326 | 0.83 | MEN1 (0.73) | MEN1KMT2AMAPTLMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116585315-A | Compositions for modulating PD-1 signaling | 奥古斯塔大学研究所公司 | 2023-08-15 | — | — | CN | claimed |
| CN-116585315-A | Compositions for modulating PD-1 signaling | 奥古斯塔大学研究所公司 | 2023-08-15 | — | — | CN | disclosed |