Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 7/20 | 1.00 |
| ▸ | MAPT | P10636 | 3/20 | 1.00 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | GAA | P10253 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 1.00 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | PLG | P00747 | 2/20 | 0.53 |
| ▸ | KLK1 | P06870 | 2/20 | 0.53 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.53 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.51 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.51 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30516144 | 1.00 | MEN1 (1.00) | MEN1KMT2AMAPTRXFP1KDM4E | |
| SCHEMBL15537171 | 1.00 | MEN1 (1.00) | MEN1KMT2AMAPTRXFP1KDM4E | |
| SCHEMBL27774119 | 0.84 | MAPT (0.72) | MEN1KMT2AMAPTRXFP1KDM4E | |
| SCHEMBL7689975 | 0.84 | KMT2A (0.72) | MEN1KMT2AMAPTRXFP1KDM4E | |
| SCHEMBL17419431 | 0.84 | MEN1 (0.72) | MEN1KMT2AMAPTRXFP1KDM4E | |
| SCHEMBL12368193 | 0.80 | MEN1 (0.66) | MEN1KMT2AMAPTRXFP1KDM4E | |
| SCHEMBL11339110 | 0.77 | MEN1 (0.68) | MEN1KMT2AMAPTRXFP1KDM4E | |
| SCHEMBL10889856 | 0.77 | MEN1 (0.78) | MEN1KMT2AMAPTRXFP1KDM4E | |
| SCHEMBL18422008 | 0.77 | LDHA (0.65) | MEN1KMT2AMAPTRXFP1KDM4E | |
| SCHEMBL31094235 | 0.77 | LDHA (0.65) | MEN1KMT2AMAPTRXFP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116585315-A | Compositions for modulating PD-1 signaling | 奥古斯塔大学研究所公司 | 2023-08-15 | — | — | CN | disclosed |