SCHEMBL30516181

SCHEMBL30516181

O=C(O)c1cc(CF)c(C(=O)O)cc1CF

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HMGB1 P09429 2/20 0.39
CXCL12 P48061 2/20 0.39
ALDH1A1 P00352 4/20 0.38
HPGD P15428 2/20 0.38
HSD17B10 Q99714 2/20 0.38
ALOX15 P16050 1/20 0.38
CYP1A2 P05177 1/20 0.38
KEAP1 Q14145 2/20 0.35
KLKB1 P03952 1/20 0.35
CTSB P07858 1/20 0.35
MMP9 P14780 1/20 0.35
DNMT1 P26358 1/20 0.35
DNMT3B Q9UBC3 1/20 0.35
DNMT3L Q9UJW3 1/20 0.35
DNMT3A Q9Y6K1 1/20 0.35
GABRP O00591 1/20 0.35
GABRD O14764 1/20 0.35
GABRA1 P14867 1/20 0.35
GABRB1 P18505 1/20 0.35
GABRG2 P18507 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27173939 0.83 ALDH1A1 (0.38) HMGB1CXCL12ALDH1A1HPGDHSD17B10
SCHEMBL26668958 0.81 DTYMK (0.42) ALDH1A1ALOX15CYP1A2CA1CA2
SCHEMBL27292206 0.78 KDM4E (0.47) ALDH1A1HSD17B10CA12CA1CA2
SCHEMBL9844569 0.78 ALDH1A1 (0.55) ALDH1A1HPGDHSD17B10CYP1A2CA12
SCHEMBL20213839 0.77 KDM4E (0.53) ALDH1A1HPGDALOX15CYP1A2KDM4E
SCHEMBL17897045 0.77 CSNK2A1 (0.55) ALDH1A1CA12CA1CA2CA7
SCHEMBL27569546 0.77 KDM4E (0.55) HMGB1ALDH1A1HPGDHSD17B10ALOX15
SCHEMBL27675905 0.77 ALDH1A1 (0.57) ALDH1A1HPGDHSD17B10CA1CA2
SCHEMBL8574539 0.77 SMN1; SMN2 (0.57) ALDH1A1HPGDHSD17B10CA1CA2
SCHEMBL15462885 0.77 CSNK2A1 (0.50) ALDH1A1CA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116371473-A Composite catalyst for olefin epoxidation reaction, preparation method and application thereof 大连理工大学宁波研究院 2023-07-04 CN claimed