SCHEMBL30516260

SCHEMBL30516260

O=C(O)Cn1c(=O)sc2cccc(Cl)c21

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.46
HTT P42858 1/20 0.46
KDM4E B2RXH2 1/20 0.42
PKM P14618 1/20 0.42
PTGDR2 Q9Y5Y4 2/20 0.41
AKR1B1 P15121 2/20 0.41
NPSR1 Q6W5P4 1/20 0.40
RXFP1 Q9HBX9 1/20 0.40
APEX1 P27695 1/20 0.40
ALDH1A1 P00352 1/20 0.39
KMT2A Q03164 1/20 0.39
MAPK1 P28482 1/20 0.39
MCL1 Q07820 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL54066 1.00 L3MBTL1 (0.46) L3MBTL1HTTKDM4EPKMPTGDR2
SCHEMBL8535915 1.00 L3MBTL1 (0.46) L3MBTL1HTTKDM4EPKMPTGDR2
SCHEMBL20837967 0.98 L3MBTL1 (0.44) L3MBTL1HTTKDM4EPKMPTGDR2
Oxalic Acid SCHEMBL1322867 0.97 L3MBTL1 (0.43) L3MBTL1HTTKDM4EPKMPTGDR2
Dimethylamine SCHEMBL30318944 0.94 L3MBTL1 (0.42) L3MBTL1HTTKDM4EPKMPTGDR2
Dimethylamine SCHEMBL22031846 0.94 L3MBTL1 (0.42) L3MBTL1HTTKDM4EPKMPTGDR2
Ether SCHEMBL10791364 0.91 L3MBTL1 (0.39) L3MBTL1HTTKDM4EPKMPTGDR2
SCHEMBL23008735 0.88 L3MBTL1 (0.42) L3MBTL1HTTKDM4EPKMNPSR1
Valine SCHEMBL17091432 0.87 PTGDR2 (0.36) L3MBTL1HTTKDM4EPKMPTGDR2
Potassium Ion SCHEMBL22031665 0.85 NPSR1 (0.39) L3MBTL1HTTKDM4EPKMNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4731195-A1 ANTAGONISTS OF THE IMIDAZOLINE-1 RECEPTOR FOR USE IN THE PREVENTION AND/OR TREATMENT OF AN AUTOINFLAMMATORY OR AUTOIMMUNE DISEASE Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.) (ES) 2026-04-29 EP claimed
WO-2025002914-A1 ANTAGONISTS OF THE IMIDAZOLINE-1 RECEPTOR FOR USE IN THE PREVENTION AND/OR TREATMENT OF AN AUTOINFLAMMATORY OR AUTOIMMUNE DISEASE CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III (F.S.P.) (ES) 2025-01-02 WO claimed
EP-4731195-A1 ANTAGONISTS OF THE IMIDAZOLINE-1 RECEPTOR FOR USE IN THE PREVENTION AND/OR TREATMENT OF AN AUTOINFLAMMATORY OR AUTOIMMUNE DISEASE Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.) (ES) 2026-04-29 EP disclosed
WO-2025002914-A1 ANTAGONISTS OF THE IMIDAZOLINE-1 RECEPTOR FOR USE IN THE PREVENTION AND/OR TREATMENT OF AN AUTOINFLAMMATORY OR AUTOIMMUNE DISEASE CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III (F.S.P.) (ES) 2025-01-02 WO disclosed
CN-116656539-B Carpesium V8 and application thereof 安徽农业大学 2024-03-22 CN disclosed
CN-117693498-A ROS-responsive captopril-cinnamaldehyde prodrugs, compositions and methods thereof 香港大学 2024-03-12 CN disclosed
CN-116656539-A Carpesium V8 and application thereof 安徽农业大学 2023-08-29 CN disclosed