Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29046102 | 1.00 | MAPK1 (0.38) | MAPK1ATMPOLBKDM4EL3MBTL1 | |
| SCHEMBL30413012 | 0.87 | KDM1A (0.38) | MAPK1ATMPOLBKDM4EL3MBTL1 | |
| SCHEMBL24215555 | 0.87 | KDM1A (0.38) | MAPK1ATMPOLBKDM4EL3MBTL1 | |
| SCHEMBL24215687 | 0.86 | ATM (0.41) | MAPK1ATMKDM4EL3MBTL1PSMD14 | |
| SCHEMBL31003355 | 0.86 | MAPK1 (0.41) | MAPK1ATMPOLBKDM4EL3MBTL1 | |
| SCHEMBL3372466 | 0.86 | MAPK1 (0.41) | MAPK1ATMPOLBKDM4EL3MBTL1 | |
| SCHEMBL25333591 | 0.86 | MAPK1 (0.35) | MAPK1ATMPOLBKDM4EL3MBTL1 | |
| SCHEMBL25933737 | 0.86 | MAPK1 (0.35) | MAPK1ATMPOLBKDM4EL3MBTL1 | |
| SCHEMBL24214158 | 0.85 | MAPK1 (0.40) | MAPK1ATMPOLBKDM4EL3MBTL1 | |
| SCHEMBL25331869 | 0.85 | MGLL (0.36) | MAPK1ATMPOLBKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116528862-A | Compounds and compositions for the treatment of diseases associated with STING activity | 艾福姆德尤股份有限公司 | 2023-08-01 | — | — | CN | disclosed |