Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 12/20 | 0.60 |
| ▸ | CYP11B2 | P19099 | 12/20 | 0.60 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.59 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25366032 | 1.00 | CYP11B1 (0.60) | CYP11B1CYP11B2MKNK1MKNK2CYP1A2 | |
| SCHEMBL4621587 | 0.85 | FYN (0.67) | CYP11B1CYP11B2MKNK1MKNK2MAP4K4 | |
| SCHEMBL486081 | 0.85 | CYP11B1 (0.58) | CYP11B1CYP11B2MKNK1MKNK2CYP1A2 | |
| SCHEMBL16675835 | 0.83 | CYP11B1 (0.78) | CYP11B1CYP11B2MKNK1MKNK2CYP1A2 | |
| SCHEMBL22084643 | 0.83 | MKNK1 (0.59) | CYP11B1CYP11B2MKNK1MKNK2CYP1A2 | |
| SCHEMBL21960161 | 0.82 | CYP11B1 (0.73) | CYP11B1CYP11B2MKNK1MKNK2CYP1A2 | |
| SCHEMBL24226868 | 0.81 | CYP11B1 (0.54) | CYP11B1CYP11B2MKNK1MKNK2CYP1A2 | |
| SCHEMBL26784208 | 0.80 | ABL1 (0.62) | CYP1A2CYP3A4CYP2C9CYP1A1CYP1B1 | |
| SCHEMBL5702666 | 0.80 | CYP1A1 (0.74) | CYP11B1CYP11B2MKNK1MKNK2CYP1A2 | |
| SCHEMBL15296276 | 0.79 | CYP11B1 (0.64) | CYP11B1CYP11B2MKNK1MKNK2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119013017-A | Pharmaceutical composition for treating cancer comprising an anticancer agent and a novel compound having an inhibitory activity on prostaglandin E2 receptor | 治纳辅医药科技有限公司 | 2024-11-22 | — | — | CN | disclosed |
| WO-2023158221-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING CANCER, COMPRISING ANTICANCER AGENT AND NOVEL COMPOUND HAVING INHIBITORY ACTIVITY WITH RESPECT TO PROSTAGLANDIN E2 RECEPTORS | 주식회사 카나프테라퓨틱스 | 2023-08-24 | — | — | WO | disclosed |
| CN-116529238-A | Novel prostaglandin E 2 Compounds with receptor inhibiting activity and uses thereof | 治纳辅医药科技有限公司 | 2023-08-01 | — | — | CN | disclosed |