Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 7/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22794821 | 0.90 | KDM4E (0.46) | KDM4ENPC1RAB9AHRH3MAPT | |
| SCHEMBL22856415 | 0.86 | DPP4 (0.41) | DPP4HRH3CYP1A2S1PR1MAOA | |
| SCHEMBL23842183 | 0.85 | DPP4 (0.40) | DPP4HRH3CYP1A2S1PR1MAOA | |
| SCHEMBL24359587 | 0.85 | HRH3 (0.45) | DPP4HRH3S1PR1MAOAMAOB | |
| SCHEMBL23696638 | 0.85 | DPP4 (0.40) | DPP4HRH3ALDH1A1 | |
| SCHEMBL25192949 | 0.84 | MAPT (0.51) | KDM4ENPC1RAB9ADPP4HRH3 | |
| SCHEMBL24093152 | 0.84 | HRH3 (0.50) | KDM4ENPC1RAB9AHRH3 | |
| SCHEMBL15037944 | 0.83 | DPP4 (0.60) | DPP4HRH3L3MBTL3L3MBTL1 | |
| SCHEMBL13169263 | 0.83 | KDM4E (0.49) | KDM4ENPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL22856542 | 0.81 | CHRM4 (0.42) | KDM4ENPC1RAB9AHRH3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116529252-A | Prodrugs for sustained release of therapeutic agents and uses thereof | 重庆两江药物研发中心有限公司 | 2023-08-01 | — | — | CN | disclosed |