Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 7/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.31 |
| ▸ | CLK1 | P49759 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.31 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24478613 | 1.00 | GRM5 (0.37) | GRM5CYP1A2ALDH1A1KDM4EMAPT | |
| SCHEMBL22714646 | 0.83 | GRM5 (0.43) | GRM5CYP1A2ALDH1A1KDM4EMAPT | |
| SCHEMBL29481383 | 0.83 | GRM5 (0.43) | GRM5CYP1A2ALDH1A1KDM4EMAPT | |
| SCHEMBL29631164 | 0.81 | GRM5 (0.34) | GRM5CYP1A2FLT3SYKAURKB | |
| SCHEMBL24478743 | 0.80 | PARP1 (0.38) | FLT3SYKAURKBNTRK1NTRK3 | |
| SCHEMBL30516699 | 0.80 | PARP1 (0.38) | FLT3SYKAURKBNTRK1NTRK3 | |
| SCHEMBL24478400 | 0.76 | USP2 (0.35) | CYP1A2ALDH1A1MAPK1 | |
| SCHEMBL29631233 | 0.76 | USP2 (0.35) | CYP1A2ALDH1A1MAPK1 | |
| SCHEMBL24478325 | 0.75 | EGFR (0.34) | PIK3CA | |
| SCHEMBL30516684 | 0.75 | EGFR (0.34) | PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116601149-A | Aminoquinazoline derivatives as P2X3 inhibitors | 奇斯药制品公司 | 2023-08-15 | — | — | CN | disclosed |