Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STIM1 | Q13586 | 2/20 | 0.63 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.63 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | STAT3 | P40763 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | GPR132 | Q9UNW8 | 8/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.41 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7893481 | 0.97 | STIM1 (0.67) | STIM1ORAI1ORAI3SMN1; SMN2LMNA | |
| Trifluoroacetic Acid SCHEMBL759110 | 0.93 | STIM1 (0.62) | STIM1ORAI1ORAI3SMN1; SMN2LMNA | |
| Trifluoroacetic Acid SCHEMBL756040 | 0.92 | STIM1 (0.66) | STIM1ORAI1ORAI3SMN1; SMN2LMNA | |
| SCHEMBL757315 | 0.90 | STIM1 (0.73) | STIM1ORAI1ORAI3SMN1; SMN2LMNA | |
| SCHEMBL30096587 | 0.90 | STIM1 (0.73) | STIM1ORAI1ORAI3SMN1; SMN2LMNA | |
| SCHEMBL10241254 | 0.88 | STIM1 (0.70) | STIM1ORAI1ORAI3SMN1; SMN2LMNA | |
| Trifluoroacetic Acid SCHEMBL756529 | 0.86 | STIM1 (0.65) | STIM1ORAI1ORAI3SMN1; SMN2LMNA | |
| SCHEMBL3063316 | 0.83 | STIM1 (0.72) | STIM1ORAI1ORAI3SMN1; SMN2LMNA | |
| SCHEMBL7893849 | 0.83 | STIM1 (0.69) | STIM1ORAI1ORAI3SMN1; SMN2LMNA | |
| SCHEMBL755563 | 0.81 | STIM1 (0.71) | STIM1ORAI1ORAI3SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100273744-A1 | COMPOUNDS | GORE PAUL MARTIN | 2010-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100273744-A1 | COMPOUNDS | LTC4S, HRH4, HRH2 | STIM1 2564/4885ORAI1 3127/4885ORAI3 2440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.