SCHEMBL305185

SCHEMBL305185

CC1(C)CC(=O)C(Br)C(=O)C1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.54
ALDH1A1 P00352 12/20 0.43
KMT2A Q03164 5/20 0.43
KDM4E B2RXH2 3/20 0.43
POLB P06746 2/20 0.43
TSHR P16473 2/20 0.43
HTT P42858 1/20 0.43
MEN1 O00255 2/20 0.38
HPGD P15428 2/20 0.38
HSD17B10 Q99714 2/20 0.38
CYP2C9 P11712 2/20 0.37
CYP3A4 P08684 1/20 0.37
LMNA P02545 1/20 0.37
CYP2C19 P33261 1/20 0.37
GAA P10253 2/20 0.35
GLA P06280 1/20 0.35
CYP1A2 P05177 1/20 0.35
HIF1A Q16665 1/20 0.35
MAOA P21397 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL3997504 0.97 MAPT (0.52) MAPTALDH1A1KMT2AKDM4EPOLB
SCHEMBL304986 0.75 MAPT (0.38) MAPTALDH1A1KMT2AKDM4EPOLB
SCHEMBL368265 0.74 MAPT (0.56) MAPTALDH1A1KMT2AKDM4EPOLB
SCHEMBL20036958 0.72 MAPT (0.54) MAPTALDH1A1KMT2AKDM4EPOLB
SCHEMBL9348170 0.72 MAPT (0.54) MAPTALDH1A1KMT2AKDM4EPOLB
SCHEMBL432006 0.72 MAPT (0.54) MAPTALDH1A1KMT2AKDM4EPOLB
SCHEMBL3536541 0.70 MAPT (0.41) MAPTALDH1A1KMT2AKDM4EPOLB
SCHEMBL11615206 0.70 MAPT (0.46) MAPTALDH1A1KMT2AKDM4EPOLB
SCHEMBL8154627 0.70 MAPT (1.00) MAPTALDH1A1KMT2AKDM4EPOLB
SCHEMBL11298803 0.70 MAPT (0.52) MAPTALDH1A1KMT2AKDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2855441-B1 IMINO COMPOUNDS AS PROTECTING AGENTS AGAINST ULTRAVIOLET RADIATIONS ELKIMIA INC (CA) 2018-04-11 EP disclosed
EP-2855441-B1 IMINO COMPOUNDS AS PROTECTING AGENTS AGAINST ULTRAVIOLET RADIATIONS ELKIMIA INC (CA) 2018-04-11 EP disclosed
US-9487474-B2 Imino compounds as protecting agents against ultraviolet radiations Elkimia, Inc. (CA) 2016-11-08 US disclosed
US-9487474-B2 Imino compounds as protecting agents against ultraviolet radiations Elkimia, Inc. (CA) 2016-11-08 US disclosed
US-9487474-B2 Imino compounds as protecting agents against ultraviolet radiations Elkimia, Inc. (CA) 2016-11-08 US disclosed
CN-104470906-B Imino compounds as protective agents against ultraviolet radiation 爱尔克米亚 2016-08-24 CN disclosed
CN-103524465-B The synthetic method of furane derivative NANJING UNIVERSITY (CN) 2015-10-28 CN disclosed
US-20150152046-A1 IMINO COMPOUNDS AS PROTECTING AGENTS AGAINTS ULTRAVIOLET RADIATIONS ELKIMIA (CA) 2015-06-04 US disclosed
US-20150152046-A1 IMINO COMPOUNDS AS PROTECTING AGENTS AGAINTS ULTRAVIOLET RADIATIONS ELKIMIA (CA) 2015-06-04 US disclosed
US-20150152046-A1 IMINO COMPOUNDS AS PROTECTING AGENTS AGAINTS ULTRAVIOLET RADIATIONS ELKIMIA (CA) 2015-06-04 US disclosed
WO-2008044022-A1 FUSED THIAZOLE DERIVATIVES AS KINASE INHIBITORS UCB PHARMA S.A. (BE) 2008-04-17 WO disclosed
EP-1885709-A2 BENZOFURAN DERIVATIVES WITH THERAPEUTIC ACTIVITIES Pharmos Corporation (US) 2008-02-13 EP disclosed
EP-1881827-A1 FUSED THIAZOLE DERIVATIVES AS KINASE INHIBITORS UCB Pharma, S.A. (BE) 2008-01-30 EP disclosed
WO-2006129318-A2 BENZOFURAN DERIVATIVES WITH THERAPEUTIC ACTIVITIES PHARMOS CORPORATION (US) 2006-12-07 WO disclosed
WO-2006114606-A1 FUSED THIAZOLE DERIVATIVES AS KINASE INHIBITORS UCB PHARMA S.A. (BE) 2006-11-02 WO disclosed
US-4380640-A PLANT GROWTH REGULATORS; 7-OXO-BENZOTHIAZOL-2-YL-N-ALKYL UREA DERIVATIVES CIBA-GEIGY CORPORATION (US) 1983-04-19 US disclosed
EP-0032879-A1 Benzothiazolyl-urea derivatives, their preparation, formulations containing them and their use as herbicides CIBA-GEIGY AG (CH) 1981-07-29 EP disclosed
US-4190606-A OF AN ALPHA-HALOGENATED CARBONYL COMPOUND BY-PRODUCT OF AN ALKENE OXIDATION USING A HYDROHALIC ACID CELANESE CORPORATION (US) 1980-02-26 US disclosed
US-4008279-A OR PREVENTION OF HALOGENATIONOXIDATION CATALYST CELANESE CORPORATION (US) 1977-02-15 US disclosed
US-3954984-A ANTISECRETRETORY AGENTS, CENTRAL NERVOUS SYSTEM DEPRESSANTS RICHARDSON-MERRELL INC. (US) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150152046-A1 IMINO COMPOUNDS AS PROTECTING AGENTS AGAINTS ULTRAVIOLET RADIATIONS ERCC4, ERCC1, RAD51 MAPT 231/4885ALDH1A1 260/4885KMT2A 2357/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.