SCHEMBL368265

SCHEMBL368265

CC1C(=O)CC(C)(C)CC1=O

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.56
ALDH1A1 P00352 11/20 0.46
KDM4E B2RXH2 2/20 0.46
GAA P10253 2/20 0.46
GLA P06280 1/20 0.46
KMT2A Q03164 5/20 0.45
POLB P06746 2/20 0.45
TSHR P16473 2/20 0.45
HTT P42858 1/20 0.45
MEN1 O00255 2/20 0.39
HPGD P15428 2/20 0.39
HSD17B10 Q99714 2/20 0.39
CYP2C9 P11712 2/20 0.38
CYP3A4 P08684 1/20 0.38
LMNA P02545 1/20 0.38
CYP2C19 P33261 1/20 0.38
CYP1A2 P05177 1/20 0.36
HIF1A Q16665 1/20 0.36
MAOA P21397 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL305185 0.74 MAPT (0.54) MAPTALDH1A1KDM4EGAAGLA
SCHEMBL432006 0.74 MAPT (0.54) MAPTALDH1A1KDM4EGAAGLA
SCHEMBL9348170 0.74 MAPT (0.54) MAPTALDH1A1KDM4EGAAGLA
SCHEMBL20036958 0.74 MAPT (0.54) MAPTALDH1A1KDM4EGAAGLA
SCHEMBL9346454 0.73 MAPT (0.38) MAPTALDH1A1KDM4EGAAGLA
SCHEMBL4701006 0.73 MAPT (0.38) MAPTALDH1A1KDM4EGAAGLA
Bromide SCHEMBL3997504 0.72 MAPT (0.52) MAPTALDH1A1KDM4EGAAGLA
SCHEMBL21247206 0.72
SCHEMBL11298803 0.72 MAPT (0.52) MAPTALDH1A1KDM4EGAAGLA
SCHEMBL8154627 0.72 MAPT (1.00) MAPTALDH1A1KDM4EGAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230147021-A1 POLYSULFIDE STABILIZATION UNIVERSITY PUBLIC CORPORATION OSAKA (JP) 2023-05-11 US disclosed
US-20190270700-A1 METHODS AND COMPOSITIONS FOR TERPENOID SYNTHESIS UNIV FLORIDA (US) 2019-09-05 US disclosed
WO-2018053322-A1 METHODS AND COMPOSITIONS FOR TERPENOID SYNTHESIS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2018-03-22 WO disclosed
CN-105254483-B A kind of method for preparing the Dicarbonyl derivatives of 2 methyl 1,3 苏州大学 2017-11-03 CN disclosed
US-8748432-B2 Microbiocidal pyrazole derivatives SYNGENTA PARTICIPATIONS AG (CH) 2014-06-10 US disclosed
US-8748432-B2 Microbiocidal pyrazole derivatives SYNGENTA PARTICIPATIONS AG (CH) 2014-06-10 US disclosed
US-8188203-B2 Intraocular lens formed from a polymer of an unsaturated aryl monoazo dye containing a 2-pyrazolin-5-one, dimedone (5,5-dimethyl-1,3-cyclohexanedione), acetoacetamide, malonamide, barbituric acid or 1,3-propanedione residue; yellow light absorbers; block ultraviolet and/or violet-blue light transmission Abbott Medical Optics Inc. (US) 2012-05-29 US disclosed
US-8188203-B2 Intraocular lens formed from a polymer of an unsaturated aryl monoazo dye containing a 2-pyrazolin-5-one, dimedone (5,5-dimethyl-1,3-cyclohexanedione), acetoacetamide, malonamide, barbituric acid or 1,3-propanedione residue; yellow light absorbers; block ultraviolet and/or violet-blue light transmission Abbott Medical Optics Inc. (US) 2012-05-29 US disclosed
EP-2261696-B1 Copolymerizable azo compounds and articles containing them ABBOTT MEDICAL OPTICS INC (US) 2012-03-14 EP disclosed
EP-2261696-A1 Copolymerizable azo compounds and articles containing them Abbott Medical Optics Inc. (US) 2010-12-15 EP disclosed
US-20040160557-A1 Article with optically modified cholesteric liquid crystal layer VAN DE WITTE PETER (NL) 2004-08-19 US disclosed
US-6723479-B2 MODIFYING CHOLESTERIC REFLECTION BAND BY EXPOSURE TO ULTRAVIOLET RADIATION; LIQUID CRYSTALS KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2004-04-20 US disclosed
EP-1278646-A1 METHOD FOR PROVIDING A SURFACE OF AN ARTICLE WITH A DECORATION OR TEXT Koninklijke Philips Electronics N.V. (NL) 2003-01-29 EP disclosed
EP-0932611-B1 METAL COMPLEXES WITH AN ADAMANTANE-LIKE STRUCTURE BASF AG (DE) 2001-12-12 EP disclosed
US-20010046015-A1 Method for providing a surface of an article with a decoration or text KONINKLIJKE PHILIPS ELECTRONICS N.V. 2001-11-29 US disclosed
WO-2001085472-A1 METHOD FOR PROVIDING A SURFACE OF AN ARTICLE WITH A DECORATION OR TEXT KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2001-11-15 WO disclosed
US-6077965-A Metal complexes with an adamantane-like structure BASF AKTIENGESELLSCHAFT (DE) 2000-06-20 US disclosed
EP-0932611-A1 METAL COMPLEXES WITH AN ADAMANTANE-LIKE STRUCTURE BASF AKTIENGESELLSCHAFT (DE) 1999-08-04 EP disclosed
WO-1998016534-A1 METAL COMPLEXES WITH AN ADAMANTANE-LIKE STRUCTURE BASF AKTIENGESELLSCHAFT (DE) 1998-04-23 WO disclosed
US-4987056-A IMPROVED SENSITIVITY TO VISIBLE LIGHT TOYO BOSEKI KABUSHIKI KAISHA (JP) 1991-01-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230147021-A1 POLYSULFIDE STABILIZATION YWHAZ, YWHAH, PTPN21 MAPT 4394/4885ALDH1A1 2635/4885KDM4E 607/4885
US-20190270700-A1 METHODS AND COMPOSITIONS FOR TERPENOID SYNTHESIS SQLE, GGPS1, LSS MAPT 4558/4885ALDH1A1 1353/4885KDM4E 1158/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.